Iris Publishers_Journal of Textile Science & Fashion Technology (JTSFT)

Imposing Application of Nano Cellulose Based Bio Sensor to Produce Test Kit of COVID: 19 Disease

Abstract

This article reflects that probable application of Nano cellulose to invent test kit of COVID: 19 diseases. It is recognized that COVID: 19 is a pandemic disease. Novel Corona virus is a mRNA virus which is enveloped by protein molecules. In the structure of corona virus, it contains protein spikes. In this conceptual article, the author predicts that Nano cellulose based test kit can detect corona virus positive in the human body. Cellulose is one of the most abundant biomass in the world. In the structure of cellulose there are lots of hydroxyl ion remain. Hydroxyl ion can give reaction with the amino acid. Authors wanted to develop a process model to make the test kit of COVID: 19 diseases. Wood is the best source of cellulose. Besides its, textile materials like cotton, flax etc are another good source of cellulose. In this article, the source of cellulose cannot play a vital role .The method of processing cellulose Nano device & reaction mechanism between hydroxyl ion & amino acid will play a significant role.

Keywords: Nanocellulsoe; Biosensors; Chromatography; Device; Point of care; Sustainable, Piezoelectric, Electrode, Electrophoresis

Introduction

Actually Nanocellulsoe is a promising natural material which is extracted from natural cellulosic source. There are varieties types of Nanocellulsoe. Like cellulose nanocrystal, Nanocellulsoe filament, bacterial cellulose is remaining in the research area. In this article author used Nano cellulose to produce test kit of COVID: 19 diseases. COVID: 19 is a pandemic disease in this world. There is a crisis of test kit in this world. This proposed model helps to experiment about the test kit. Nanocellulose is a cost effective advanced material which is used for biodegradability & low cytotoxicity. Advanced Nanocellulsoe was used for producing test kit of HIV virus, Ebola virus & hepatitis C virus [1].Professor Whiteside’s research group invented cellulose based point of care molecular devices at Harvard University [1]. Prediction goes that this process is applicable for making test kit of COVID: 19 diseases. Cellulose is a sustainable material source which can be extracted from cotton, wood, bacteria. Nanocellulose has a great mechanical characteristics .Actually the mechanical characteristics depend on the source of extraction [3].

Structural Analysis of Novel Corona Virus

Corona virus has four genera .They are: alpha corona virus, beta corona virus, gamma corona virus& delta corona virus. Alpha & beta corona virus create infection to the mammals. Gamma corona virus can affect the avian species. Delta corona virus can infect both mammals & avian species. Corona virus is a large enveloped, positive standard RNA virus. The genome sequence is 27-32 KB. In the structure of corona virus helical capsid is surrounded by nucelocapsid protein. There are three types of protein in novel corona virus. Membrane protein, envelope protein, spikes protein (Figure 1).

From the observation of American National Institute of Health spike protein is tractable to boggle hole the human cells to produce COVID: 19 diseases [2]. This proposed model can help to identify spike protein of novel corona virus . Proposed test kit can identify spike protein from insulating antibodies of people .Schematic diagram of SARS-COV-2 virus (novel corona) virus is given below (Figure 2).

Besides the biomedical application of Nano cellulose has been used for some special functions. One of the functions is detecting the disease or acting as a diagnostic device. Actually it is a cellulose based device which is called point of care molecular device. These systems are low cost, lightweight, hydrophilic & porous. This device is revealed by renewable material & rehashes them to appropriate compact lab - on systems. The device is originally disclosed by the stamping patterns, channels & trial zones by involving a fragment of paper. The process of this Nano cellulose based point of core medical device is giving a biological sample like blood, urine & saliva are applied to the diagnosis media through a special device. The paper collisions the sample through the ducts to trial zones to mode the biochemical reaction. It is known to all Nano cellulose is a piezoelectric material [4]. It can change its electrical polarization during mechanical stress. The sensors are generally joined by sandwiching Nano cellulose between two electrodes. Due to piezoelectric approach, when blood, saliva etc are given in the trial zone an external force is created to the Nano cellulose film, then it changes electrical polarization & getting signal by sandwiched sensors. Finally chromatography method is used to diagnosis the disease (Figure 3).

Biochemical Reaction of Amino acid of Spike Protein & Hydroxyl ion of Nanocellulose

We all know that the PH of blood is 7.4. It’s a basic medium actually. When the patient will give the blood in Nano cellulose based device, it takes reaction between amino acid of spike protein & hydroxyl group of Nano cellulose. As blood is a basic medium reaction will be occurred following way (Figure 4).

For More Open Access Journals in Iris Publishers Please Click on: https://irispublishers.com/

For More Information:https://irispublishers.com/jtsft/fulltext/imposing-application-of-nano-cellulose-based-bio-sensor-to-produce-test-kit-of-covid-19-disease.ID.000621.php 


Comments

Post a Comment

Popular posts from this blog

Saturated Fatty Acids Derivatives as Assistants Materials for Textile Processes

Image
  Abstract Many auxiliaries have been used in textile industries in dry or wet processes. One of the important based materials is fatty acids and its derivatives. The present work aims at preparing some textile auxiliaries based on saturated fatty acids. Six different materials were used to react with each fatty acid. Produced materials have been characterised using FT-IR, HLB and cloud point. Based on the HLB values, produced materials have been used as softeners or as O/W emulsifiers (printing paste). Treated fabrics with softeners show a very good physical and mechanical properties and printed fabrics with prepared pastes shows a good printing paste with good prints characteristics (colour strength and colour fastness). Read More About this Article:  https://irispublishers.com/jtsft/fulltext/saturated-fatty-acids-derivatives-as-assistants-materials-for-textile-processes.ID.000516.php Read More Iris Publishers Google Scholar Articles :  https://scholar.google.com/citati...
Read more

Modern Fibers: A Human- Centered Technology

Image
Textile Science and Fashion Technology Clothing represents one of the most ancient forms of human expression and is a tool that an individual use to express his/her culture and social status in society. Since the dawn of civilization, humans have used fabrics to provide basic warmth and show aesthetics. People gradually added more patterns and styles, creating clothing out of different materials. Today, the U.S. fashion and apparel industry are a $12 billion business, with the average American family spending $1,700 on clothes annually (BLS Data 2018) [1]. The fiber sector of the clothing and textile industry has undergone substantial change in recent years, and the modern fibers have opened a whole new frontier for clothing products. Modern fibers, also known as smart fibers, are becoming a human-centered technology. The smart fabrics will have the capability to see, hear, and sense their surroundings and to respond to the external stimulus through an active control mechanis...
Read more

The Rain Maker

Image
Opinion On the bottom floor of the Besse Library and across the Media Center is a room that either most people probably don’t pay attention to or always wonder what it contains. The room holds thousands of stories from all over the country, dating from over a century ago to the present day. These stories are not limited to paper and a bound cover but by thread and fabric. They all help create the Historic Costume Study Collection. Upon entering the cold room, you might feel overwhelmed. On the wall to the left are shelves that contain purses, hats, and muffs; on the right, there are shoes, gloves, and jewelry in cabinets and in repurposed library catalog card holders. Of course, you cannot overlook the mountain of garment boxes reaching up to the ceiling. The back wall has the fur and extensive wedding gown sections. Clothing racks are placed in messy rows that make maneuvering around difficult. The Historic Costume Study Collection has all you could ever need and want from fashion. Th...
Read more